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(Rac)-PEAQX

Product Specifications

UNSPSC Description

(Rac)-PEAQX is a NMDA receptor agonist. (Rac)-PEAQX can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures [1].

Target Antigen

Apoptosis; Caspase; iGluR

Type

Reference compound

Related Pathways

Apoptosis;Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-peaqx.html

Smiles

O=C1C(NC2=C(C(C(P(O)(O)=O)NC(C3=CC=C(Br)C=C3)C)=CC=C2)N1)=O

Molecular Weight

454.21

References & Citations

[1]Annabel Romero-Hernandez, et al. Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077. Mol Pharmacol

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12294B/Rac-PEAQX-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12294B/

Clinical Information

No Development Reported

CAS Number

2514919-70-9

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