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Mequindox

Mequindox is an antimicrobial agent[1]. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice[2].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mequindox.html

Concentration

10mM

Purity

99.62

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=C(C)[N+]([O-])=C2C=CC=CC2=[N+]1[O-])=O

Molecular Formula

C11H10N2O3

Molecular Weight

218.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Qianying Liu, et al. Mequindox Induced Genotoxicity and Carcinogenicity in Mice. Front Pharmacol. 2018 Apr 10;9:361.|[2]Qianying Liu, et al. Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse. Front Pharmacol. 2018 May 1;9:436.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131102/Mequindox-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131102/Mequindox-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[13297-17-1]

Available Sizes

Curated Selection

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