Adriforant
PF-3893787 is a novel histamine H4 receptor antagonist binding affinity (Ki=2.4 nM) and is also a functional (Ki=1.56 nM) antagonist.
Product Specifications
CAS Number
[943057-12-3]
Product Name Alternative
PF-3893787
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/adriforant.html
Smiles
NC1=NC(N2C[C@H](NC)CC2)=CC(NCC3CC3)=N1
Molecular Formula
C13H22N6
Molecular Weight
262.35
References & Citations
[1]Mowbray CE, et al. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21 (21) :6596-602.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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