Adriforant
Product Specifications
UNSPSC Description
PF-3893787 is a novel histamine H4 receptor antagonist binding affinity (Ki=2.4 nM) and is also a functional (Ki=1.56 nM) antagonist.
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/adriforant.html
Smiles
NC1=NC(N2C[C@H](NC)CC2)=CC(NCC3CC3)=N1
Molecular Weight
262.35
References & Citations
[1]Mowbray CE, et al. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19705/Adriforant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19705/
Clinical Information
Phase 2
CAS Number
943057-12-3
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