Neomycin (sulfate) (Standard)
Product Specifications
UNSPSC Description
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2].
Target Antigen
Antibiotic; Bacterial; Phospholipase
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/neomycin-sulfate-standard.html
Smiles
O[C@H]1[C@H](O)[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]4N)[C@H]3O)O[C@@H]1CN.[3H2SO4]
Molecular Weight
908.88
References & Citations
[1]Sasseville D. Neomycin. Dermatitis. 2010;21(1):3-7.|[2]Hu GF. Neomycin inhibits angiogenin-induced angiogenesis. Proc Natl Acad Sci U S A. 1998;95(17):9791-9795.|[3]Sasseville D. Neomycin. Dermatitis. 2010;21(1):3-7.|[4]Hu GF. Neomycin inhibits angiogenin-induced angiogenesis. Proc Natl Acad Sci U S A. 1998;95(17):9791-9795.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0470R/Neomycin-sulfate-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0470R/
CAS Number
1405-10-3
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