(S) -Higenamine
(S) -Higenamine ((S) -Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S) -Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) [1].
Product Specifications
CAS Number
[22672-77-1]
Product Name Alternative
(S) -Norcoclaurine
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-higenamine.html
Solubility
10 mM in DMSO
Smiles
OC1=CC2=C([C@H](CC3=CC=C(O)C=C3)NCC2)C=C1O
Molecular Formula
C16H17NO3
Molecular Weight
271.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282 (9) :6274‐6282.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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