ERK-MYD88 interaction inhibitor 1
Product Specifications
UNSPSC Description
ERK-MYD88 interaction inhibitor 1 is an ERK-MYD88 interaction inhibitor. ERK-MYD88 interaction inhibitor 1 can induce an HRI-mediated integrated stress response (ISR), leading to cancer cell-specific immunogenic cell apoptosis (apoptosis). ERK-MYD88 interaction inhibitor 1 can induce anti-tumor T cell responses in Lewis lung cancer mice, exhibiting anti-tumor activity[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk-myd88-interaction-inhibitor-1.html
Smiles
CN(C)C(C=C1)=CC=C1C2=NC3=CC(C(NC4=CN=C(OC)C=C4)=O)=CC=C3N2
Molecular Weight
387.43
References & Citations
[1]Virard F, et al. Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death. Nat Commun. 2024 Aug 15;15(1):7037.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162863/ERK-MYD88-interaction-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162863/
Clinical Information
No Development Reported
CAS Number
2215927-89-0
Curated Selection
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