L-Glutamic γ-monohydroxamate
Product Specifications
UNSPSC Description
L-Glutamic γ-monohydroxamate is an antitumor agent, inhibits cell proliferation. L-Glutamic γ-monohydroxamate selectively inhibits the uptake of L-histidine into microvascular endothelial cell. L-Glutamic γ-monohydroxamate, as a vanadium ligand, activates glucose uptake and metabolism, thus decreases the blood glucose levels in vivo[1][2][3].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-glutamic-γ-monohydroxamate.html
Smiles
N[C@H](C(O)=O)CCC(NO)=O
Molecular Weight
162.14
References & Citations
[1]Vila J, et al. In vitro and in vivo anti-tumor activity of L-glutamic acid gamma-monohydroxamate against L1210 leukemia and B16 melanoma. Int J Cancer. 1990 Apr 15;45(4):737-43.|[2]Sakurai E, et al. Stereoselective transport of histidine in rat lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1192-7.|[3]Goldwaser I, et al. L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo. J Biol Chem. 1999 Sep 10;274(37):26617-24.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137874/L-Glutamic-γ-monohydroxamate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137874/L-Glutamic-γ-monohydroxamate-SDS-MedChemExpress.pdf
CAS Number
1955-67-5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
