(+)-Afzelechin
Product Specifications
UNSPSC Description
(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia[1].
Target Antigen
Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/plus-afzelechin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1
Molecular Weight
274.272
References & Citations
[1]Junichi Saijyo, et al. Alpha-glucosidase Inhibitor From <i>Bergenia Ligulata</i>. J Oleo Sci. 2008;57(8):431-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2821/plus-Afzelechin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2821/plus-Afzelechin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2545-00-8
Available Sizes
Curated Selection
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