ML307
ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research[1].
Product Specifications
CAS Number
[3058650-52-2]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ml307.html
Purity
99.10
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NCC1CCN(CC2=CC(Cl)=CC=C2)CC1)[C@@H]3CCCN(C4=NC=NC5=C4N=C6CCCCN65)C3
Molecular Formula
C28H36ClN7O
Molecular Weight
522.08
References & Citations
[1]Robert Ardecky, et al. Selective UBC 13 Inhibitors. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2010.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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