Chk2-IN-2
Chk2-IN-2 (compound 2) is a selective inhibitor of CHK2 with potential anticancer activity[1].
Product Specifications
CAS Number
[2984543-29-3]
UNSPSC
12352005
Target
Checkpoint Kinase (Chk)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/chk2-in-2.html
Smiles
FC1=C(C2=NC(C(N[C@H]3C[C@@H](CNC3)F)=O)=C(N=C2)N)C=C(C4=CN(N=C4)CC(F)(F)F)N=C1
Molecular Formula
C20H19F5N8O
Molecular Weight
482.41
References & Citations
[1]Preparation of 3-aminopyrazine-2-carboxamide derivatives and use thereof for inhibiting checkpoint kinase 2. World Intellectual Property Organization, WO2023177233 A1 2023-09-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk2
Curated Selection
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