WEE1-IN-7
Product Specifications
UNSPSC Description
WEE1-IN-7 (compound 12h) is a potent and orally activeWEE1 inhibitor with an IC50 value of 2.1 nM. WEE1-IN-7 induces apoptosis and cell cycle arrest at the S phase. WEE1-IN-7 shows antitumor activity[1].
Target Antigen
Apoptosis; Wee1
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wee1-in-7.html
Smiles
O=C1C2=CN=C(NC3=CC=C(N4CCN(CC4)C)C=C3)N=C2N(N1CC=C)C5=CC=CC(C6=NC=CN=C6)=N5
Molecular Weight
520.59
References & Citations
[1]Wang Y, et al. Advanced Design, Synthesis, and Evaluation of Highly Selective Wee1 Inhibitors: Enhancing Pharmacokinetics and Antitumor Efficacy. J Med Chem. 2024 Jun 7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163697/WEE1-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163697/
Clinical Information
No Development Reported
CAS Number
2924006-98-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
