Irigenin (Standard)
Product Specifications
UNSPSC Description
Irigenin (Standard) is the analytical standard of Irigenin. This product is intended for research and analytical applications. Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1].
Target Antigen
Apoptosis; Integrin
Type
Reference Standards
Related Pathways
Apoptosis;Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/irigenin-standard.html
Smiles
O=C1C(C2=CC(OC)=C(OC)C(O)=C2)=COC3=CC(O)=C(OC)C(O)=C13
Molecular Weight
360.31
References & Citations
[1]Amin A, et al. Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells. Sci Rep. 2016 Nov 16;6:37151.|[2]Xu Y, et al. Irigenin sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells. Biochem Biophys Res Commun. 2018 Feb 12;496(3):998-1005.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2587R/Irigenin-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2587R/
CAS Number
548-76-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7099538 Inquire
Recombinant Prorocentrum micans Photosystem Q (B) protein (psbA), partial
Ask
View Details 
ARP32711_P050-Biotin 100 µL
MYT1 Antibody - N-terminal region: Biotin (ARP32711_P050-Biotin)
Ask
View Details