Anticancer agent 188
Product Specifications
UNSPSC Description
Anticancer agent 188 (compound D43) inhibits DNA synthesis in TNBC cells, leading to cell cycle arrest at the G2/M phase. Anticancer agent 188 has anti-cancer viability by inducing ROS-mediated apoptosis and DNA damage[1].
Target Antigen
DNA/RNA Synthesis; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-188.html
Solubility
10 mM in DMSO
Smiles
CN1C(C2=NC(C3=C(F)C=CC=C3)=N1)=NC(N(C)C2=O)=O
Molecular Weight
287.25
References & Citations
[1]Tingyue Wu, et al. Toxoflavin analog D43 exerts antiproliferative effects on breast cancer by inducin. Sci Rep. 2024, 14, 1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162276/Anticancer-agent-188-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162276/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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