trans-Isoferulic acid (Standard)
Product Specifications
UNSPSC Description
trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[1].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[2].
Target Antigen
NO Synthase; Prostaglandin Receptor
Type
Reference Standards
Related Pathways
GPCR/G Protein;Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trans-isoferulic-acid-standard.html
Smiles
O=C(O)/C=C/C1=CC=C(OC)C(O)=C1
Molecular Weight
194.19
References & Citations
[1]Kai-Hui Sun, et al. A new indole-type alkaloid from the roots of <i>Clematis florida var. plena</i>. Nat Prod Res. 2019 Oct;33(20):2925-2931.|[2]Matharage Gayani Dilshara, et al. Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1. Int Immunopharmacol. 2014 Jan;18(1):203-11.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0761AR/trans-Isoferulic-acid-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0761AR/
CAS Number
25522-33-2
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