CP-20961

CP-20961 is an interferon inducer. CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2][3].

Product Specifications

CAS Number

[35607-20-6]

Product Name Alternative

Avridine

UNSPSC

12352211

Target

IFNAR

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cp-20961.html

Purity

98.34

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

OCCN(CCO)CCCN(CCCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCC

Molecular Formula

C43H90N2O2

Molecular Weight

667.19

References & Citations

[1]Brun JG, et al. Effects of calprotectin in avridine-induced arthritis. APMIS. 1995 Mar;103 (3) :233-40.|[2]Vingsbo C, et al. Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. Clin Exp Immunol. 1995 Mar;99 (3) :359-63.|[3]Stinnett JD, et al. Synthetic immunomodulators for prevention of fatal infections in a burned guinea pig model. Ann Surg. 1983 Jul;198 (1) :53-7.|[4]Chang YH, et al. Adjuvant polyarthritis. IV. Induction by a synthetic adjuvant: immunologic, histopathologic, and other studies. Arthritis Rheum. 1980 Jan;23 (1) :62-71.|[5]Wing EJ, et al. Dissociative effects of a novel immunomodulating agent (CP-20, 961) on host defenses of mice. J Immunopharmacol. 1984;6 (4) :339-58. |[6]Waldman RH, et al. Effect of CP-20,961, an interferon inducer, on upper respiratory tract infections due to rhinovirus type 21 in volunteers. J Infect Dis. 1978;138 (4) :531-535.