HCGb Antibody / HCG-beta

Human chorionic gonadotropin antibody (hCG) is a glycoprotein hormone synthesized in syncytiotrophoblastic cells of placenta and in certain trophoblastic tumors. The hormone-specific alpha chains have molecular weights of 13 kDa. HCG is found in moles and choriocarcinoma, chorionic components of germ cell tumors, and syncytiotrophoblast like cells in seminoma/dysgerminoma and embryonal carcinoma. In diagnostic pathology, hCG is a useful marker for classification of germ cell tumors, identification of extragonadal germ cell tumors.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P01233

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant human partial protein was used as the immunogen for the HCGb antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

HCGb/4709R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the HCGb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HCGb antibody is available for research use only.

Storage Conditions

Aliquot the HCGb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the HCGb antibody should be determined by the researcher.

Location

Cytoplasm, secreted

Image Legend

IHC staining of FFPE human placental tissue with HCGb antibody (HCGb/4709R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.