FBN1 Antibody

Fibrillin-1 / FBN1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and non-elastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P35555

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 330-476 was used as the immunogen for the FBN1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

FBN1/2191

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the FBN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FBN1 antibody is available for research use only.

Storage Conditions

Aliquot the FBN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the FBN1 antibody should be determined by the researcher.

Location

Extracellular matrix

Image Legend

IHC staining of FFPE human placental tissue with FBN1 antibody (clone FBN1/2191) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.