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PI-103

PI-103 is a multi-targeted inhibitor of PI3K for p110, p110, p110 , and p110 with reported IC50 values of 2 nM, 3 nM, 3 nM, and 15 nM respectively. PI-103 is less potent towards mTOR/DNA-PK with reported IC50 values of 30 nM and 23 nM respectively.

Product Specifications

Purity

≥ 98%

Format

Crystalline solid

Solubility

Soluble in DMSO or DMF at approximately 10 mg/mL. Poorly soluble in aqueous solutions. If necessary, first solubilize in DMSO or DMF and dilute into an aqueous solution, such as PBS.

Molecular Formula

C19H16N4O3

Shipping Conditions

Room Temperature

Storage Conditions

At least 2 years as supplied at -20°C. At least 6 months in DMSO at -80°C. Do not store aqueous solutions for longer than one day.

Calculated Molecular Weight

348.36 kDa

CAS Number

371935-74-9

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