Hydroxyebastine
Product Specifications
UNSPSC Description
Hydroxyebastine is an Ebastine (HY-B0674) (a histamine H1-receptor antagonist) metabolite. Hydroxyebastine is metabolized to Carebastine (HY-121356) by CYP2J2 and CYP3A4[1].
Target Antigen
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hydroxyebastine.html
Smiles
O=C(CCCN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C(C)(CO)C)C=C4
Molecular Weight
485.66
References & Citations
[1]Liu KH, et al. Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A. Drug Metab Dispos. 2006 Nov;34(11):1793-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122508/Hydroxyebastine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122508/
Clinical Information
No Development Reported
CAS Number
210686-41-2
Curated Selection
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