Pafenolol
Product Specifications
UNSPSC Description
Pafenolol is a selectively oral-active β1 adrenergic receptor (β1-adrenergic receptor) antagonist that effectively lowers blood pressure. Pharmacokinetic studies in rats indicate that the absorption of Pafenolol is influenced by gastrointestinal contents, with food intake reducing the bioavailability of Pafenolol in rats. Pafenolol can be used in research related to cardiovascular diseases and asthma[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pafenolol.html
Smiles
CC(C)NC(NCCC1=CC=C(C=C1)OCC(O)CNC(C)C)=O
Molecular Weight
337.46
References & Citations
[1]Sigurdsson J A, et al. Pafenolol, a new β 1-selective blocking agent, in mild hypertension. Result of an inpatient study and a subsequent outpatient follow-up[J]. European journal of clinical pharmacology, 1984, 26: 549-553.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-165495/Pafenolol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-165495/
Clinical Information
No Development Reported
CAS Number
75949-61-0
Curated Selection
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