p120 Catenin Antibody / CTNND1 / Catenin delta 1
Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.
Product Specifications
UniProt
O60716
Host
Mouse
Immunogen
A portion of amino acids 138-276 was used as the immunogen for the Delta 1 Catenin antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Delta 1 Catenin antibody is available for research use only.
CAS Number
9007-83-4
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