TMEPAI Recombinant Antibody / PMEPA1
PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Product Specifications
UniProt
Q96W9
Host
Mouse
Immunogen
Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant PMEPA1 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant PMEPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant PMEPA1 antibody is available for research use only.
CAS Number
9000-83-3
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