CD79b Antibody
The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA: 2-4 µg/mL (order BSA-azide free format for coating)
UniProt
P40259
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
IGB/2940R
Type
Recombinant
Applications
ELISA
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the CD79b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD79b antibody is available for research use only.
Storage Conditions
Aliquot the CD79b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CD79b antibody should be determined by the researcher.
Location
Cell surface
Image Legend
SDS-PAGE analysis of purified, BSA-free CD79b antibody (clone IGB/2940R) as confirmation of integrity and purity.
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