Amyloid beta Antibody / APP
Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
Product Specifications
UniProt
P05067
Host
Mouse
Immunogen
A portion of amino acids 578-680 from the human protein was used as the immunogen for the Amyloid Beta antibody.
Clonality
Monoclonal
Isotype
IgG2c κ
Applications
IF, FACS, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Amyloid Beta antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Amyloid Beta antibody is available for research use only.
CAS Number
9007-83-4
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