Type I Cytokeratin Recombinant Antibody (CK10/14/15/16/19)
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.
Product Specifications
UniProt
Q7Z794
Host
Rabbit
Immunogen
A portion of amino acids 100-200 from Type I Cytokeratins was used as the immunogen for the recombinant Type I Cytokeratin antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant Type I Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Type I Cytokeratin antibody is available for research use only.
CAS Number
9000-83-3
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