CD137 Recombinant Antibody / 4-1BB / TNFRSF9
CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
Product Specifications
UniProt
Q07011
Host
Mouse
Immunogen
A portion of amino acids 19-188 from the human protein was used as the immunogen for the recombinant CD137 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant CD137 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD137 antibody is available for research use only.
CAS Number
9000-83-3
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