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TdT Antibody

Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. It is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.

Product Specifications

UniProt

P04053

Host

Mouse

Immunogen

A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

ELISA, IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the TdT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This TdT antibody is available for research use only.

CAS Number

9007-83-4

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