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Herpes Virus 8 Antibody

HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.

Product Specifications

Host

Rat

Immunogen

Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.

Clonality

Monoclonal

Isotype

IgG2c κ

Applications

ELISA, IF, IHC-P

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the human HHV8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This HHV8 antibody is available for research use only.

CAS Number

9007-83-4

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