MUC1 Antibody / Mucin-1
MAb VU-11D1 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU-11D1 is the 7-mer TSAPDTR of the MUC1 tandem repeat as established with 'epitope fingerprinting'. The'extra cellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating)
UniProt
P15941
Host
Mouse
Reactivity
Human
Immunogen
Human breast cancer cell line ZR-75 cells were used as the immunogen for this MUC1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
VU-11D1
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the MUC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This MUC1 antibody is available for research use only.
Storage Conditions
Store the MUC1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the MUC1 antibody should be determined by the researcher.
Image Legend
SDS-PAGE analysis of purified, BSA-free MUC1 antibody (clone VU-11D1) as confirmation of integrity and purity.
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