SOX2 Recombinant Antibody
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]
Product Specifications
UniProt
P48431
Host
Rabbit
Immunogen
Amino acids 176-305 were used as the immunogen for the recombinant SOX2 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant SOX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant SOX2 antibody is available for research use only.
CAS Number
9000-83-3
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