Melanoma Cell Marker Antibody Cocktail (anti-MART-1 + gp100 + Tyrosinase)
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
UniProt
Q16655 (Melan-A), P14679 (Tyrosinase), P40967 (gp100)
Host
Mouse
Immunogen
Clonality
Monoclonal
Isotype
IgG1 + IgG2a
Applications
IHC-P, WB
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Melanoma Cell Marker antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Melanoma Marker antibody cocktail is available for research use only.
CAS Number
9007-83-4
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