TMEPAI Antibody / PMEPA1
PMEPA1 (prostate transmembrane protein, androgen induced 1), or TMEPAI (Transmembrane prostate androgen induced protein) is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1/TMEPAI interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of TMEPAI is observed in prostate tumors, suggesting that TMEPAI may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Product Specifications
UniProt
Q969W9
Host
Mouse
Immunogen
Full-length recombinant human protein was used as the immunogen for the TMEPAI antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
IHC-P
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the TMEPAI antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TMEPAI antibody is available for research use only.
CAS Number
9007-83-4
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