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TRP1 / Tyrosinase-Related Protein-1 Antibody

Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]

Product Specifications

UniProt

P17643

Host

Mouse

Immunogen

Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Applications

IHC-P

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This TRP1 antibody is available for research use only.

CAS Number

9007-83-4

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