Aurora B Antibody / AURKB
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
Product Specifications
UniProt
Q96GD4
Host
Mouse
Immunogen
Amino acids 89-251 were used as the immunogen for this AURKB antibody.
Clonality
Monoclonal
Isotype
IgG1
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This AURKB antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6698929/datasheet/v3927-20ug.pdf
CAS Number
9007-83-4
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