TLE1 Antibody
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. [UniProt]
Product Specifications
UniProt
Q04724
Host
Mouse
Immunogen
A portion of amino acids 175-338 from the human protein was used as the immunogen for the TLE1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Applications
IHC-P, WB
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the TLE1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TLE1 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6698839/datasheet/v3890-20ug.pdf
CAS Number
9007-83-4
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