Integrin alpha E Antibody / CD103
This antibody recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E-beta-7 integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. This antibody is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
Product Specifications
UniProt
P38570
Host
Mouse
Immunogen
A portion of amino acids 775-855 from the human protein was used as the immunogen for the CD103 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD103 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD103 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6698691/datasheet/v3837-100ug.pdf
CAS Number
9007-83-4
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