Integrin beta 3 Recombinant Antibody / ITGB3 / CD61
CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.
Product Specifications
UniProt
P05106
Host
Rabbit
Immunogen
Human recombinant protein was used as the immunogen for the recombinant CD61 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the recombinant CD61 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD61 antibody is available for research use only.
CAS Number
9000-83-3
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