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EpCAM Antibody

EGP40 is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Product Specifications

UniProt

P16422

Host

Mouse

Immunogen

A human recombinant partial protein corresponding to amino acids 100-224 (extracellular domain) was used as the immunogen for the Ep-CAM antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Applications

ELISA, FACS, IF, IF, IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the Ep-CAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Ep-CAM antibody is available for research use only.

CAS Number

9007-83-4

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