SPTBN2 Antibody / Spectrin beta III
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin α and spectrin β are present in erythrocytes, whereas spectrin αII (fodrin α) and spectrin βI (fodrin β) are present in other somatic cells. SPTBN2/Spectrin βIII is highly homologous to both spectrin βI and spectrin βII. SPTBN2 is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.
Product Specifications
UniProt
O15020
Host
Mouse
Immunogen
Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
FACS, IF, WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Spectrin beta III antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Spectrin beta III antibody is available for research use only.
CAS Number
9007-83-4
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