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VCAM-1 Antibody

Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.

Product Specifications

UniProt

P19320

Host

Mouse

Immunogen

Recombinant human protein was used as the immunogen for the VCAM1 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the VCAM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This VCAM1 antibody is available for research use only.

CAS Number

9007-83-4

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