ABO Antibody / Blood Group Antigen A
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 2-4 µg/mL, Immunohistology (formalin-fixed) : 1-2 µg/mL for 30 min at RT
UniProt
P16442
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgM k
Clone
HE-193
Applications
IH, IF
Purity
PEG precipitation
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the ABO antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This ABO antibody is available for research use only.
Storage Conditions
Store the ABO antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Cell surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with Blood Group Antigen A antibody (HE-193)
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