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CEA Antibody / Carcinoembryonic Antigen

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This mAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Product Specifications

UniProt

P06731

Host

Mouse

Immunogen

Recombinant full-length human protein was used as the immunogen for the CEA antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

IHC-P

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the CEA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CEA antibody is available for research use only.

CAS Number

9007-83-4

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