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CD14 Antibody

Recognizes a protein of 55kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

Product Specifications

UniProt

P08571

Host

Mouse

Immunogen

Human CD14/LPSR recombinant protein was used as immunogen for this CD14 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Applications

FACS, IF

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

CD14 antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.

Limitations

This CD14 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6694485/datasheet/v2418-100ug.pdf

CAS Number

9007-83-4

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