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Fibroblast Growth Factor 23 / FGF-23 Antibody

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Product Specifications

Host

Mouse

Immunogen

A recombinant human FGF-23 protein was used as the immunogen for this antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

ELISA, Functional studies

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the FGF-23 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This FGF-23 antibody is available for research use only.

CAS Number

9007-83-4

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