EGF Receptor / EGFR Antibody
This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. <a href=../search_result.php?search_txt=egfr>EGFR</a> is type I receptor tyrosine kinase with sequence homology to <a href=../search_result.php?search_txt=erbb2>ErbB2</a>, -3 -4 or <a href=../search_result.php?search_txt=her2>HER2</a>, -3 -4. It binds to Epidermal Growth Factor (EGF), <a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa)</a>, Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Product Specifications
Host
Mouse
Immunogen
Microsomes from A431 cells were used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Applications
Affinity purification, Blocking, Inhibition, IP, FACS
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the EGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This EGF Receptor antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6693721/datasheet/v2106-20ug.pdf
CAS Number
9007-83-4
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