CD34 Antibody
This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but shows low specificity.
Product Specifications
Host
Mouse
Immunogen
Blast cells from a chronic myeloid leukemia patient were used as the immunogen for this CD34 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
FACS
Format
PE Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD34 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Limitations
This antibody is available for research use only.
CAS Number
9007-83-4
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