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CD147 / Emmprin / Basigin Antibody

This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

Host

Mouse

Immunogen

Human T cell line Molt-13 was used as the immunogen for this CD147 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

Functional testing, FACS, IF, IHC-P

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the CD147 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD147 antibody is available for research use only.

CAS Number

9007-83-4

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