Gbp2 Antibody / Guanylate-binding protein 2

Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene. This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP) . The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q9Z0E6

Host

Rabbit

Reactivity

Mouse

Immunogen

An E. coli-derived mouse protein (amino acids R181-L589) was used as the immunogen for the Gbp2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the Gbp2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Gbp2 antibody is available for research use only.

Storage Conditions

After reconstitution, the Gbp2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Gbp2 antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of mouse ANA-1 cells with Gbp2 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Gbp2 antibody.