SAMHD1 Antibody

SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

Q9Y3Z3

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein (amino acids E37-M626) was used as the immunogen for the SAMHD1 antibody.

Clonality

Monoclonal

Isotype

IgG2b

Clone

10H8

Applications

WB, IHC-P, IF, FACS

Purity

Antigen affinity purified

Format

Purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the SAMHD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SAMHD1 antibody is available for research use only.

Storage Conditions

After reconstitution, the SAMHD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SAMHD1 antibody should be determined by the researcher.

Location

Nuclear

Image Legend

IHC staining of FFPE human ovarian serous adenocarcinoma tissue with SAMHD1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.